Chronic stress increases bone resorption in apical periodontitis stress and endodontic disease in rats
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چکیده
منابع مشابه
Disodium chlodronate prevents bone resorption in experimental periodontitis in rats.
BACKGROUND Periodontitis is a chronic disease characterized by alveolar bone loss and inflammatory changes. We studied the effect of disodium chlodronate (CD), a bisphosphonate used in metastatic and metabolic bone disease as a bone resorbing drug, in an experimental periodontitis model (EPD) focusing on anti-resorptive and anti-inflammatory parameters. METHODS A nylon thread ligature was pla...
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Objective(s): Association of adolescent emotional stress (ES) with the incidence of cardiovascular disease (CVD) at older age was investigated. Materials and Methods: 21 female rats were divided into three groups of 7 each; ES, foot-shock, and control. Chronic ES was induced by exposing the rats to witness foot-shock of their neighboring...
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BACKGROUND Porphyromonas gingivalis has been shown to invade osteoblasts and inhibit their differentiation and mineralization in vitro. However, it is unclear if P. gingivalis can invade osteoblasts in vivo and how this would affect alveolar osteoblast/osteoclast dynamics. This study aims to answer these questions using a periodontitis mouse model under repetitive P. gingivalis inoculations. ...
متن کاملMechanisms of Bone Resorption in Periodontitis
Alveolar bone loss is a hallmark of periodontitis progression and its prevention is a key clinical challenge in periodontal disease treatment. Bone destruction is mediated by the host immune and inflammatory response to the microbial challenge. However, the mechanisms by which the local immune response against periodontopathic bacteria disturbs the homeostatic balance of bone formation and reso...
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Abstract Introduction: Chronic heterogeneous stress may be better for evaluation of the effect of chronic stress situations on the nociceptive behaviour. The present study investigated the effects of chronic heterogeneous sequential stress on thermal-induced nociception and formalin induced pain behavior in rats. Methods: In the present study, adult rats (220-300 g) were used. Animals were ...
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ژورنال
عنوان ژورنال: Oral Biology and Dentistry
سال: 2013
ISSN: 2053-5775
DOI: 10.7243/2053-5775-1-2